HuBMAP Funded Research
HuBMAP is divided into five categories based on the type of work being undertaken by each group. These are the currently funded components that make up the HuBMAP Consortium.
These research groups come from universities and institutions across the United States and the globe, and have formed meaningful partnerships with one another to begin building the human body atlas.
HuBMAP Infrastructure, Visualization & Engagement
The HIVE contains several teams: two Mapping Components which are responsible for building an atlas of tissue maps; two Tools Components, which are developing novel tools for visualizing, searching and modelling data; and the IEC (Infrastructure, Engagement and Communications) which manages and maintains the HuBMAP infrastructure and the data generated by the Consortium and coordinates internal and external Consortium activities.
HIVE groups are based at:
Rapid Technology Implementation
The RTIs focus on enhancing, large-scale validation, and integration of emerging new technologies into the HuBMAP Consortium. Their goal is to improve the quality and throughput of atlas generation at key steps of the production pipeline including sample collection, tissue mapping, and data integration and analysis.
RTIs are based at:
Tissue Mapping Centers
TMCs collect and analyze a range of normal tissues from both male and female donors with a variety of ages and ethnicities. The samples collected range from discrete, complex organs through distributed organ systems and systems comprising dynamic or motile cell types with distinct microenvironments. The organs being studied include the bladder, kidney/ureter, colon, lung, lymph nodes, spleen, thymus, pancreas, eye, uterus, fallopian tubes, ovaries, tooth, cartilage, heart, bone and vasculature.
TMCs are based at:
Battelle Pacific Northwest Laboratories
Beth Israel Deaconess Medical Center
Children's Hospital of Philadelphia
General Electric/ University of Pittsburgh
Johns Hopkins University
Stanford University / Bone marrow
UC San Diego / Female Reproductive System
University of Connecticut / Scripps Research Institute
University of Florida
University of Pennsylvania
University of Rochester Medical Center
Vanderbilt University / Kidney
Vanderbilt University/ Pancreas and Eye
Washington University in St. Louis
Transformative Technology Development
TTDs collect and analyze tissue along with the TMCs, including tissue from the heart, aorta, skin, kidney, endothelial cells, liver, pancreas, uterus, and breast. TTDs also provide proof-of-principle with initial validation of transformative new tools, techniques and methods for mapping the human body at high resolution.
TTDs are based at:
DPs work to enable improved access and utility of the reference datasets available from HuBMAP. They demonstrate how HuBMAP resources, in combination with other datasets or biospecimens, can be used to build better statistical and analytic tools and models of cellular organization and communication in tissues.
DPs are based at: