Spatial Biology – The New Frontier | June 16-17, 2026 | Rockville, MD

SPATIAL BIOLOGY 2026 AGENDA

Meeting Goals:

  • Enable practical use of spatial maps for disease mechanism discovery, translational and clinical studies
  • Lower barriers for community data integration and spatial map expansion
  • Address new challenges and explore the next frontier for spatial biology

Themes:

  • Practical use of spatial maps to generate and test hypotheses describe microenvironments of functional tissue units (3D)
  • Is it representative?: How do you know to trust the most complex integration of spatial data?
  • Making good time: Biology across the lifespan (4D)
  • On the basis of sex: Discovering sex differences to understand health and disease
  • New and emerging platforms for spatial analyses for preclinical and translational use

June 16 Tuesday 2026

TimeTopic / Speaker
8:00 – 8:15amWelcome
8:15 – 9:00amKeynote – Dr. Xiaowei Zhuang:
    Spatially resolved single-cell genomics and functional genomics.
9:00 – 9:15amBREAK
9:15 – 10:55am     Practical use of spatial maps to generate and test hypotheses describe microenvironments of functional tissue units (3D).
9:15 – 9:45amDr. Rahul Satija:
    Organismal-scale integration and annotation of single-cell and spatial data.
9:45 – 10:15amDr. Gloria Pryhuber:
    Defining Microenvironments of Airway and Submucosal Gland Functional Tissue Units Through Multimodal Spatial Mapping.
10:15 – 10:35amDr. Shuoshuo Wang, Beth Israel Deaconess Medical Center:
    From Surgical Specimen to Spatial Insight: A Technical Framework for Biobanking and Mapping Functional Lymphatic Microenvironments.
10:35 – 10:55amDr. Geremy Clair, PNNL:
    Spatial omics technologies have revealed novel cellular and molecular changes in BPD and IPF lungs.
10:55 – 11:05amBREAK
11:05 – 11:35amDr. Katalin Susztak:
    Building a Trustworthy Kidney Spatial Atlas: Cross-Platform Validation, Clinical Correlation, and Translational Readout in DKD.
11:35 – 12:05amDr. Sylvia K. Plevritis:
    Mapping Metastatic Niches and Treatment Resistance with Spatial Community, Colocalization, and Spatiotemporal Modeling.
12:05 – 1:05pmLunch
1:05 – 2:00pmIs it representative?: How do you know to trust the most complex integration of spatial data?
1:05 – 1:25pmEric Cramer, Oregon Health and Science University:
    Bridging Agent-Based Simulation and Clinical Spatial Profiling with a Tumor-Immune Dynamic Landscape.
1:25 – 1:45pmDr. Andreas Bueckle, Indiana University:
    Spatial Maps as Exploration Tools: Emerging VR Platforms for 3D Tissue Microenvironments.
1:45 – 2:00pm BREAK
2:00 – 3:40pmMaking good time: Biology across the lifespan (4D)
2:00 – 2:30pmDr. Sanjay Jain:
    What Does Molecular Cartography Teach Us About Human Kidney Organization, Function, and Disease Mechanisms?
2:30 – 3:00pmDr. Rong Fan:
    Seeing RNA Biology in Action in Human Tissues.
3:00 – 3:20pmDr. Abdalla Ahmed, Stanford University:
    Temporal and Spatial Profiling of the Aging Human Intestine at Single Cell Resolution Reveals Epigenetic Regulators of Aging.
3:20 – 3:40pmYang Miao, Duke University:
    Age-related cell type abundance changes, senescence marker expression gradients, and age-related spatial pattern changes in the healthy human colon.
3:40pmAdjourn
3:40 – 4:30pmBREAK - FREE TIME
4:30 – 7:00pmPoster session at the hotel
    Recommended poster dimensions: 4' long by 3' tall, STANDARD POSTER size.
5:00 – 6:00pmThemes 1 and 2
6:00 – 7:00pmThemes 3. 4, and 5

June 17 Wednesday 2026

TimeTopic / Speaker
8:00 – 9:40amOn the basis of sex: Discovering sex differences to understand health and disease
8:15 – 8:45amDr. Hongkui Zeng:
    Brain Cell Type and Cell State Dynamics.
8:45 – 9:15amDr. Noël Burtt:
    CFDE Liver Resource
9:15 – 9:35am Dr. Peiran Lu, Children’s Hospital of Philadelphia:
    Spatially resolved, multidimensional atlas offers new insights into the molecular and spatial heterogeneity of the human heart.
9:35 – 9:55amDr. Diane Saunders, Lurie Children’s Hospital of Chicago:
    Mapping the cellular and extracellular organization of the human ovary across the lifespan by single-cell transcriptomics and multiplex antibody-based imaging.
10:00 – 10:20am BREAK
10:20am – 12:00pmNew and emerging platforms for spatial analyses, for preclinical and translational use
10:20 – 10:50amDr. Beth McQuiston:
    Translating diagnostic tests to clinical care: Insights from Industry.
10:50 – 11:20amDr. Chris Larsen:
    From Signal to Standard of Care: Translating Discoveries into Clinical Practice.
11:20 – 11:40amRosa Nguyen, University of California, Los Angeles:
    Photonic Single-nucleus Indexing Profiling of the Genome, 3D Genome Conformation, and Epigenomes.
11:40am – 12:00pmDr. Lieke Michielsen, Cornell University:
    View of spatial variation for individual cell types.
12:00 – 1:00pmLunch
1:00 – 2:00pm Round Table: What are the next steps?
2:00 – 2:45pm Keynote – Dr. Garry Nolan:
    Using Large Language Models to Understand the Tumor-Immune Interface.
2:45pm Final Words from Organizers and Adjourn