Spatial Biology – The New Frontier | June 16-17, 2026 | Rockville, MD

SPATIAL BIOLOGY 2026 AGENDA

Meeting Goals:

  • Enable practical use of spatial maps for disease mechanism discovery, translational and clinical studies
  • Lower barriers for community data integration and spatial map expansion
  • Address new challenges and explore the next frontier for spatial biology

Themes:

  • Practical use of spatial maps to generate and test hypotheses describe microenvironments of functional tissue units (3D)
  • Is it representative?: How do you know to trust the most complex integration of spatial data?
  • Making good time: Biology across the lifespan (4D)
  • On the basis of sex: Discovering sex differences to understand health and disease
  • New and emerging platforms for spatial analyses for preclinical and translational use

June 16 Tuesday 2026

TimeTopic / Speaker
8:00 – 8:15amWelcome
8:15 – 9:00amKeynote – Dr. Xiaowei Zhuang
9:00 – 9:15amBREAK
9:15 – 10:55am Practical use of spatial maps to generate and test hypotheses describe microenvironments of functional tissue units (3D).
9:15 – 9:45amDr. Rong Fan
9:45 – 10:15amDr. Gloria Pryhuber
10:15 – 10:35amDr. Shuoshuo Wang, Broad Institute
From Surgical Specimen to Spatial Insight: A Technical Framework for Biobanking and Mapping Functional Lymphatic Microenvironments.
10:35 – 10:55amDr. Geremy Clair, PNNL
Spatial omics technologies have revealed novel cellular and molecular changes in BPD and IPF lungs.
11:15am – 1:15pmLunch and Poster Session
1:15 – 2:55pmIs it representative?: How do you know to trust the most complex integration of spatial data?
1:15 – 1:45pmDr. Katalin Susztak
1:45 – 2:15pmDr. Sylvia K. Plevritis
2:15 – 2:35pmEric Cramer, Oregon Health and Science University
Bridging Agent-Based Simulation and Clinical Spatial Profiling with a Tumor-Immune Dynamic Landscape.
2:35 – 2:55pmDr. Andreas Bueckle, Indiana University
Spatial Maps as Exploration Tools: Emerging VR Platforms for 3D Tissue Microenvironments.
3:00 – 3:15pm BREAK
3:15 – 4:55 pmMaking good time: Biology across the lifespan (4D)
3:15 – 3:45pmDr. Sanjay Jain
3:45 – 4:15pmDr. Rahul Satija
4:15 – 4:35pmDr. Abdalla Ahmed, Stanford University
Temporal and Spatial Profiling of the Aging Human Intestine at Single Cell Resolution Reveals Epigenetic Regulators of Aging.
4:35 – 4:55pmYang Miao, Duke University
Age-related cell type abundance changes, senescence marker expression gradients, and age-related spatial pattern changes in the healthy human colon.
5:00pmAdjourn for Day 1

June 17 Wednesday 2026

TimeTopic / Speaker
8:00 – 9:40amOn the basis of sex: Discovering sex differences to understand health and disease
8:15 – 8:45amDr. Hongkui Zeng
8:45 – 9:15amDr. Noël Burtt
9:15 – 9:35am Dr. Peiran Lu, Children’s Hospital of Philadelphia
Spatially resolved, multidimensional atlas offers new insights into the
molecular and spatial heterogeneity of the human heart.
9:35 – 9:55amDr. Diane Saunders, Lurie Children’s Hospital of Chicago
Mapping the cellular and extracellular organization of the human ovary across the lifespan by single-cell transcriptomics and multiplex antibody-based imaging.
10:00 – 10:20am BREAK
10:20am – 12:00pmNew and emerging platforms for spatial analyses, for preclinical and translational use
10:20 – 10:50amDr. Beth McQuiston
10:50 – 11:20amDr. Chris Larsen
11:20 – 11:40amDr. Rosa Nguyen, University of California, Los Angeles
PSI-seq offers insight into regulatory mechanisms underlying tumor progression and microenvironmental remodeling.
11:40am – 12:00pmDr. Lieke Michielsen, Cornell University
View of spatial variation for individual cell types.
12:00 – 2:00pmLunch and Poster Session
2:00 – 3:00pm Round Table: What are the next steps?
3:00 – 3:45pm Keynote – Dr. Garry Nolan
3:45pm Final Words from Organizers and Adjourn