HuBMAP Happenings 1/14/2020

HuBMAP Happenings 1/14/2020
January 14, 2020
Data Security Plan and Data Sharing Plan

The IEC invites all HuBMAP Consortium members to  review and comment on the recently completed Data Security Plan and Data Sharing Plan for HuBMAP . Please add comments directly to the Google Docs for the  Data Security Plan and Supporting Documents  (including an Acceptable Use Policy and Incident Response Policy and Procedures), and the  Data Sharing Plan   by the end of the day on Tuesday January 28.

*Note that these are links to folders that contain these documents so members can see them all together in context, rather than sharing individual links to each document. 
Data Use Agreement

Investigators, the DUE revision has been open for comment since January 7. All recommended edits have been made.

Here is the link to the DRAFT document to be vetted by Institution Officials as quickly as possible. Once we have received those comments, the draft will be taken to a Final Form and sent out for signature. Our previous experience is that IOs may have requirements that we should address before having all Consortium Members sign a final agreement. It is really important that you have this document reviewed by your Institution, now. Deadline for comments will be January 21 . If your IO is unable to make this deadline, please let Gloria know.

The major changes in the DUA document are provision for identified data to be shared within the HuBMAP Consortium for the purpose of de-identification and the removal of the list of HuBMAP member Institutions to be replaced by a Signatory page with tracking of Consortium members and their institutions who have signed off on the DUA. This would prevent us from having to amend and resign a DUA document each time that there is a change in Membership. Further explanation is provided as comments in the google doc, please review and comment.

Single Cell Day

Rahul Satija’s group at NYU Genome Center is hosting another Single Cell Genomics Day this year on Friday January 24. As they have in the past, the presentations will be live-streamed. These events have been very good in past years and judging by the lineup of topics and speakers, this year will likely not be an exception.
You can find out more info and connect to the event via the link here .
Requests for Application

Subject:  New Investigator Projects on 4D Nucleome Organization and Function in Human Health and Disease
Dear Investigator,
You may be interested in a new NIH Common Fund Request for Applications (RFA):  RFA-RM-20-006 , “New Investigator Projects on 4DN Organization and Function in Human Health and Disease (U01 Clinical Trial Not Allowed).” The purpose of this RFA is to support projects from scientists who are in the early stages of establishing an independent research career that apply new or existing tools to monitor and/or manipulate the 4D nucleome (4DN) in the context of human health and disease. Any human disease or biological process relevant to NIH’s mission may be proposed including environmental exposures or studies across development or lifespan.
This initiative is part of Phase 2 of the  4DN   Common Fund  program. Programs supported by the NIH Common Fund address emerging scientific opportunities and pressing challenges in biomedical research that no single NIH Institute or Center can address on its own, but are of high priority for the NIH as a whole. Common Fund programs are intended to change paradigms, develop innovative tools and technologies, and/or provide fundamental foundations for research that can be used by the broad biomedical research community. The goal of the 4DN program is to study the three-dimensional organization of the nucleus in space and time. Phase 2 of the 4DN program will focus on the roles of chromosome organization in health and disease, chromatin dynamics and function, and the development of new approaches to modeling and visualizing the spatial and temporal organization of the nucleus.
Important Funding Opportunity Information
Application receipt date: March 2, 2020
Letter of Intent due date: 30 days prior to application due date.
Budget: Application budgets may not exceed $400,000 in direct costs in any one year.
Award Project Period: The maximum project period is 5 years.
Eligibility: Eligible PIs for RFA-RM-20-006 must be an investigator(s) who has not yet competed successfully for a substantial, competing NIH independent research award. Interested PI(s) who are not eligible to this FOA should instead apply to the companion Funding Opportunity Announcement,  RFA-RM-20-005 .
Frequently Asked Questions for potential Phase 2 4DN applicants: .

There will be a pre-application webinar for potential 4DN Phase 2 applicants on January 21, 2020 at 1:00 pm Eastern Time.  The webinar is expected to last for 2 hours.
Join here and follow the WebEx instructions: 
Audio connection : 1-650-479-3207 Call-in toll number (US/Canada)
Access code : 733 412 130
Participation in the webinar, although encouraged, is optional and is not required for the submission of an application. Following the Webinar, the slides will be posted here.
Potential applicants to RFA-RM-20-006 are  strongly  encouraged to reach out to the scientific contact, Lisa Postow (  ), to discuss the alignment of their proposed work with the goals of this RFA.

Recent Publications

Kristin Burnum-Johnson from Julia Laskin’s lab published this paper in Nature. There is also an article written about the work in the PNNL newsletter, found here .

Upcoming Meetings & Events

DRT Portal call will be held Wednesday, January 15 @ 10AM ET. 

Tissue, Technology, and Data Collection working group meeting will take place Tuesday, January 21 @ 2PM ET.

Save the Date - Annual HuBMAP Meeting will take place May 18 - 20, 2020 in Bethesda, MD. Agenda and venue TBD.


Doctor: "Your DNA is backwards."

Me: "And?"

Content Suggestions

The IEC is seeking to collect information of general interest from individual members and groups and to share with the rest of the Consortium. Please submit content suggestions by emailing .
Past Newsletters are available on the Collaboration Portal .

Don’t forget to follow the Consortium on Twitter @_hubmap and mention us in any relevant tweets/retweets so we can share the great work that our members are doing!

For comments, suggestions about how to improve the HuBMAP happenings, or questions about the consortium, please contact:
Collaboration Portal