It’s time for HuBMAP’s Image of the Week! Liz McDonough from Fiona Ginty’s lab at GE Research used Cell DIVE imaging to map 9 markers (DAPI: blue, Cytokeratin_AE1: red, CD3: cyan, Collagen IV: yellow, DDB2: lime, Fibronectin: light blue, Ki67: magenta, Cadherin_pan: lavender, Smooth Muscle Actin: green, Vimentin: purple) in a hair follicle. You can see collagen, fibronectin, blood vessels, and some immune cells. It makes our hair stand on end with excitement!
Data Analysis and Visualization Day (Dec. 14/15) Reminders:
The ability to view protein molecules in cells and monitor changes in their structure, quantity, distribution, and interactions is key to understanding what causes diseases and to finding treatments and cures. The Chan Zuckerberg Initiative invites applications for its new Visual Proteomics Imaging Request for Applications (RFA) focused on supporting innovations in technology that will allow researchers to obtain near-atomic resolution readouts inside cells.
This grant program aims to advance the field of visual proteomics through 2.5-year challenge grants that will support the development of hardware, software, and methods. Examples of research themes could include hardware and software development to enhance contrast and resolution for electron tomography, high-resolution correlated light and electron microscopy (CLEM), and FIB-SEM; sample preparation improvements for electron tomography; and development of software or new computational techniques and algorithms for identifying protein molecules inside cells and segmenting sub-cellular structures.
There are two new exciting funding opportunities within HuBMAP:
HuBMAP Jumpstart Program
HuBMAP Underrepresented/Minority Student Internship Program
The Jumpstart program is designed to enable junior investigators, who are already part of HuBMAP, to work on small projects that align with the overall goals of the program. Completed applications will be accepted through December 15. Please return completed applications to firstname.lastname@example.org.
The Underrepresented/Minority Student Internship Program endeavors to provide underrepresented and minority undergraduate students (as defined by NIH) opportunities to undertake mentored scientific research in an established HuBMAP Lab. For HuBMAP Labs interested in mentoring student(s) virtually, please complete the expression of interest form and return it to email@example.com by December 15.
Additional information about both of these programs can be found on the Member Portal.
NCI Innovation Lab on Modeling Emergent Cellular Behaviors in Cancer
The application deadline has been extended for the upcoming Innovation Lab. The National Cancer Institute is hosting an Innovation Lab to generate creative strategies and new research collaborations aimed at improving understanding, prediction, and validation of dynamic cell-cell communication and emergent behaviors of cell ensembles in cancerous tissues. This 5-day virtual event will take place in February 25-26 and March 1-2 and 5, 2021. PI-level cancer researchers and clinician scientists, cell and developmental biologists, systems biologists, evolutionary biologists, engineers, physical scientists, and computer scientists, etc. are strongly encouraged to apply.
Visit the Member Portal for additional detail about each working group and to sign up.
Working Group co-chairs will be presenting updated working group charters at the upcoming Steering Committee meeting on December 7. These presentations will outline working group goals and activities for the future.
Help Desk Holiday Hours
Please note that the HuBMAP help desk will be operating on reduced hours so our team can celebrate the holidays and have some time to recharge.
Winter Break Dates:
December 24 - January 3.
Reminders, Links to Resources, etc.
If you've been following our jokes this year, here's a summary of our favorite ones:
Developers in need of HIVE infrastructure may request access through the PSC web form, found here.
Instructions for using HIVE infrastructure can now be found in the "Quick Links" section of the Collaboration Portal. A direct link to this documentation can be foundhere. Please report any issues or direct any questions firstname.lastname@example.org.
The IEC is seeking to collect information of general interest from individual members and groups to share with the rest of the Consortium. Please submit content suggestions by emailing: email@example.com.
Past Newsletters are available on the Collaboration Portal.
For comments, suggestions about how to improve the HuBMAP Happenings, or questions about the consortium, please contact: firstname.lastname@example.org